2013 Fiscal Year Final Research Report
Regulation of species--dependent calcium oscillations during fertilization in mammals
| Project/Area Number |
24780272
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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| Research Institution | Azabu University |
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Principal Investigator |
ITO JUNYA 麻布大学, 獣医学部, 准教授 (30454143)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 受精 |
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| Research Abstract |
We succeeded in molecular cloning of horse PLCz. We also showed that horse PLCz has higher activity compared to those in other mammalian species studied to date. As for the regulation of IP3R in pig oocytes, inhibition of polo-like kinase 1(Plk1) dramatically decreased the expression level of IP3R, suggests that Plk1 is involved in the regulation of IP3R expression at least in pig oocytes.
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Research Products
(9 results)
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[Journal Article] Vitrification procedure decreases inositol 1,4,5-trisphophate receptor expression, resulting in low fertility of pig oocytes2013
Author(s)
Masahiko Hirose, Maki Kamoshita, Katsuyoshi Fujiwara, Tsubasa Kato, Ayaka Nakamura, Richard Wojcikiewicz, Jan B. Parys, Junya Ito, Naomi Kashiwazaki
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Journal Title
Animal Science Journal
Volume: 84
Pages: 693-701
DOI
Peer Reviewed
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[Journal Article] The effect of M-phase stage-dependent kinase inhibitors on inositol 1,4,5-trisphosphate receptor 1 (IP_3R1) expression and localization in pig oocytes
Author(s)
Anucha Sathanawongs, Katsuyoshi Fujiwara, Tsubasa Kato, Masahiko Hirose, Maki Kamoshita, Richard J.H. Wojcikiewicz, Jan B. Parys, Junya Ito, Naomi Kashiwazaki
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Journal Title
Animal Science Journal
Volume: (in press)
Peer Reviewed
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