2014 Fiscal Year Final Research Report
An Innovative synthesis of quinoxalinones and its application to the construction of pharmacophore templates
| Project/Area Number |
24790030
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
|
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 含窒素複素環 |
|---|
| Outline of Final Research Achievements |
An efficient method for constructing quinoxalinone-N-oxides from cyanoacetanilides has been developed. This transformation can be achieved
using inexpensive reagents and molecular oxygen under mild conditions, thus offering a practical pathway to quinoxalinone-containing
pharmaceuticals such as ataquimast, caroverine, and opaviraline.
|
| Free Research Field |
有機化学
|
