2013 Fiscal Year Final Research Report
Evaluation of environmental contaminations and occupational exposures involved in chemotherapeutic drugs
| Project/Area Number |
24790152
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical pharmacy
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 職業性曝露 / 抗がん剤 / LC-MS/MS / 多成分同時分析 / エアサンプリング |
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| Research Abstract |
In this research, multicomponent high-performance liquid chromatography/tandem mass spectrometry analysis of ten chemotherapeutic drugs was newly developed and validated, and was adapted to two different types of external exposure studies. In addition, evaluable system of drug volatilities was newly developed, and intended to further internal exposure studies, simultaneous quantification of unchanged and metabolized drug was developed.
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