2014 Fiscal Year Final Research Report
Effects of lipoprotein lipase and apolipoprotein AII on exercise regimen for obesity.
| Project/Area Number |
24790320
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pathological medical chemistry
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| Research Institution | Akita University (2014)
Saga University (2012-2013) |
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Principal Investigator |
NISHIJIMA Kazutoshi 秋田大学, バイオサイエンス教育・研究センター, 准教授 (70435874)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 遺伝子導入ウサギ / アポリポ蛋白AII / リポ蛋白リパーゼ / メタボリック症候群 / 運動 |
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| Outline of Final Research Achievements |
Lactate threshold in apolipoprotein (apo)AII transgenic (Tg) rabbit tended to be lower than in lipoprotein lipase (LPL)-Tg and wild-type rabbits.
Within intravenous glucose tolerance test, decreasing rate of blood glucose level was high in LPL-Tg rabbit and low in apoAII-Tg in comparison to wild-type rabbit. After feeding high fat diet and exercise loading, the decreasing rate of blood glucose level in apoAII-Tg rabbit was lower than that in LPL-Tg and wild-type rabbits.
These results would be caused by transferred apoAII or LPL gene.
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| Free Research Field |
実験動物学
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