2013 Fiscal Year Final Research Report
Role of microRNA in cystic fluid of ovarian clear cell adenocarcinoma
Project/Area Number |
24790349
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Human pathology
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Research Institution | The University of Tokyo |
Principal Investigator |
MAEDA Daichi 東京大学, 医学部附属病院, 助教 (30585500)
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Project Period (FY) |
2012-04-01 – 2014-03-31
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Keywords | 卵巣明細胞腺癌 / 嚢胞内容液 / マイクロRNA |
Research Abstract |
We succeeded in evaluating microRNAs in the cystic fluid of ovarian neoplasm. miR-21 and miR-141 were more abundant in the cystic fluid of ovarian clear cell adenocarcinoma in comparison with their precursor lesion, endometriotic cyst. This finding suggests that miR-21 and miR-141 may play a significant role in the tumorigenesis of ovarian clear cell adenocarcinoma. Furthermore, they may be useful diagnostic markers.
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Research Products
(6 results)
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[Journal Article] Claudin-18 overexpression in intestinal-type mucinous borderline tumour of the ovary2013
Author(s)
Koso T, Matsusaka K, Tanaka M, Arimoto T, Oda K, Kawana K, Yano T, Fujii T, Fukayama M, Halimi SA, Maeda D, Shinozaki-Ushiku A
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Journal Title
Histopathology
Volume: 63(4)
Pages: 534-44
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[Presentation]2013
Author(s)
Maeda D and Fukayama M
Organizer
The 17th Taiwan-Japan-Korea Joint Meeting for Gynecological Pathology,Slide conference, Session 2, J-2
Place of Presentation
Seoul,Korea
Year and Date
2013-10-17