Prospective Randomized Trial to Evaluate Secondary Prevention with Optimized Medical Therapy for Patients with Ischemic Heart Disease

2013 Fiscal Year Final Research Report

• Project/Area Number: 24790538
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied pharmacology
• Research Institution: Keio University
• Principal Investigator: ENDO AYAKA 慶應義塾大学, 医学部, 共同研究員 (50464821)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Keywords: 虚血性心疾患 / 至適薬剤 / 臨床薬理学

Research Abstract

In the present study, we planned a multicenter, prospective, randomized study to evaluate secondary prevention with optimized medical therapy for patients with ischemic heart disease in Japan. We founded the secretariat of this study that was related with the secretariat of JCD-KICS in our university. University and participating hospital were started to register onto the Internet-based database system after study protocol was approved by the IRB committee at each site. In addition, several times a year, we were currently providing meeting to each participating sites and try to discuss the registration system and research. We analyzed data that was related with this theme from JCD-KICS database that was linked. The results of these studies have been presented in the Scientific Sessions of the national and international and manuscripts are submitted to journals. We continue to register patients in this study and analyze to quantify its long-term contribution to improved outcome.

Research Products

• [Journal Article] Anatomical variations affect radial artery spasm and procedural achievement of transradial cardiac catheterization (2014)
  • Author(s): Numasawa Y, Kawamura A, Kohsaka S, Takahashi M, Endo A, Arai T, Ohno Y, Yuasa S, Maekawa Y, Fukuda K
  • Journal Title: Heart Vessels Volume: 29(1) Pages: 49-57
  • DOI: 10.1007/s00380-013-0324-3
• [Journal Article] Disparity in the application of guideline - based medical therapy after percutaneous coronary intervention : analysis from the Japanese prospective multicenter registry (2013)
  • Author(s): Endo A, Kohsaka S, Miyata H, Kawamura A, Noma S, Suzuki M, Koyama T, Ishikawa S, Momiyama Y, Nakagawa S, Sueyoshi K, Takagi S, Takahashi T, Sato Y, Ogawa S, Fukuda K
  • Journal Title: Am J Cardiovasc Drugs Volume: 13(2) Pages: 103-12
  • DOI: 10.1007/s40256-013-0021-8
• [Journal Article] Left main trunk perforation sealed by 90 second perfusion balloon inflation (2012)
  • Author(s): Mogi S, Endo A, Kawamura A
  • Journal Title: J Invasive Cardiol Volume: 24(6) Pages: E115-8
• [Journal Article] Detection of attenuated plaque in stable angina with 64 - multidetector computed tomography : a comparison with intravascular ultrasound (2012)
  • Author(s): Jinzaki M, Okabe T, Endo A, Kawamura A, Koga S, Yamada M, Fukuda K, Kuribayashi S
  • Journal Title: Circ J Volume: 76(5) Pages: 1182-9
• [Journal Article] Successful percutaneous coil embolization of coronary-pulmonary, - carotid, and - internal mammary artery fistulas (2012)
  • Author(s): Numasawa Y, Kawamura A, Hashimoto S, Endo A, Yuasa S, Maekawa Y, Kuribayashi S, Fukuda K
  • Journal Title: Heart Vessels Volume: 27(3) Pages: 331-6
• [Presentation] When the size really matters (2013)
  • Author(s): Ayaka Endo, Kenki Ashida, Yu Yamasaki, Naoki Hirata, Tasuku Hasegawa, Toshiyuki Takahashi, Susumu Nakagawa
  • Organizer: Endovascular Cardiac Complications Conference
  • Place of Presentation: Lausanne, Switzerland
  • Year and Date: 2013-06-20
• [Presentation] Complication of Aortocoronary Dissection During PCI Resolved by Coronary Stenting (2013)
  • Author(s): Ayaka Endo, Kenki Ashida, Yu Yamasaki, Naoki Hirata, Tasuku Hasegawa, Toshiyuki Takahashi, Susumu Nakagawa
  • Organizer: Euro PCR
  • Place of Presentation: Paris, France
  • Year and Date: 2013-05-23
• [Presentation] for the JCD-KICS Investigators. Impact of Angiographical Lesion Complexity Score and In-Hospital Outcome after Percutaneous Coronary Intervention : Analysis from Japanese Multicenter Registry (2012)
  • Author(s): Ayaka Endo, Shun Kohsaka, Hiroaki Miyata, Akio Kawamura, Shigetaka Noma, Masahiro Suzuki, Takashi Koyama, Shiro Ishikawa, Yukihiko Momiyama, Susumu Nakagawa, Koichiro Sueyoshi, Shunsuke Takagi, Toshiyuki Takahashi, Yuji Sato, Satoshi Ogawa, Keiichi Fukuda
  • Organizer: TCT Conference
  • Place of Presentation: Florida, USA
  • Year and Date: 2012-10-23
• [Presentation] for the JCD-KICS Investigators. Angiographical Lesion Complexity Score and In - Hospital Outcome after Percutaneous Coronary Intervention : Analysis from JCD-KICS Multicenter Registry (2012)
  • Author(s): Ayaka Endo, Shun Kohsaka, Hiroaki Miyata, Akio Kawamura, Shigetaka Noma, Masahiro Suzuki, Takashi Koyama, Shiro Ishikawa, Yukihiko Momiyama, Susumu Nakagawa, Koichiro Sueyoshi, Shunsuke Takagi, Toshiyuki Takahashi, Yuji Sato, Satoshi Ogawa, Keiichi Fukuda
  • Organizer: Euro PCR
  • Place of Presentation: Paris, France
  • Year and Date: 2012-05-18
• [Book] 救急・集中治療 : 循環器薬の知識と使い方(25巻3・4号) (2013)
  • Author(s): 遠藤彩佳
  • Total Pages: 8(291-298)
  • Publisher: 総合医学社