Silent cerebrovascular lesions of the elderly and longitudinal decline of higher-level daily functions.

2015 Fiscal Year Final Research Report

• Project/Area Number: 24790654
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine (including Psychosomatic medicine)
• Research Institution: Tohoku University
• Principal Investigator: Tomita Naoki 東北大学, 大学病院, 助教 (00552796)
• Co-Investigator(Renkei-kenkyūsha): TSUBOTA Megumi 岩手医科大学, 医学部, 講師 (20419998) ; SATOH Michihiro 東北大学, 大学病院, 特別研究員(PD) (70717892) ; OHKUBO Takayoshi 帝京大学, 医学部, 教授 (60344652)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 大脳白質病変 / 無症候性脳梗塞 / 脳萎縮 / 無症候性脳出血 / 脳微小出血 / 手段的ADL / 老年症候群

Outline of Final Research Achievements

At the community-based cohort, both lacunar infarcts and white matter hyperintensity were significantly associated with the decline of higher-level daily functions after 7-year follow-up. Lacunar infarcts were strongly associated with the decline, rather than white matter hyperintensity. Lacunar infarcts were related to decline in intellectual activity.

Free Research Field

老年医学