2013 Fiscal Year Final Research Report
Capsule endoscpy analysis of ulcerative colitis
Project/Area Number |
24790716
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Gastroenterology
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Research Institution | Yokohama City University |
Principal Investigator |
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Project Period (FY) |
2012-04-01 – 2014-03-31
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Keywords | 潰瘍性大腸炎 / カプセル内視鏡 |
Research Abstract |
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by diffuse mucosal inflammation, traditionally regarded as being limited to the colorectum. Although several gastoroduodenal lesions have also been reported recently in cases of UC, in general, small-bowel lesions in UC are believed to be extremely rare. The aim of this study was to examine the small bowel by capsule endoscopy in patients with UC. The frequency of small-bowel lesions, the number of small-bowel lesions per patient and the capsule endoscopy score were comparatively evaluated.Almost 60% showed small-bowel lesions, and 35% had erosions. There were significant differences in the frequency of the small-bowel lesions (p < 0.001) and erosions (p = 0.009) compared with healthy volunteer. The capsule endoscopy score was correlated with the UC disease activity index (r = 0.718, p < 0.001). It was concluded that UC, a chronic inflammatory bowel disease, can also involve the small bowel.
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[Journal Article] Risk factors for small-bowel mucosal breaks in chronic low-dose aspirin users : data from a prospective multicenter capsule endoscopy registry2014
Author(s)
Endo H, Sakai E, Taniguchi L, Kessoku T, Komiya Y, Ezuka A, Kawamura H, Taguri M. Higurashi T, Ohkubo H, Yamada E, Takahashi H, Inamori M, Maeda S, Sakaguchi T, Hata Y, Nagase H, Nakajima A
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Journal Title
Gastrointest Endosc
Volume: pii: S0016-5107(14)
Pages: 01292-9
Peer Reviewed
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[Journal Article] Visceral obesity as a risk factor for left-sided diverticulitis in Japan : a multicenter retrospective study2013
Author(s)
Yamada E, Ohkubo H, Higurashi T, Sakai E, Endo H, Takahashi H, Uchida E, Tanida E, Izumi N, Kanesaki A, Hata Y, Matsuura T, Fujisawa N, Komatsu K, Maeda S, Nakajima A
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Journal Title
Gut Liver
Volume: 7(5)
Pages: 522-8
Peer Reviewed
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[Journal Article] Factors predicting the presence of small bowel lesions in patients with obscure gastrointestinal bleeding2013
Author(s)
Sakai E, Endo H, Taniguchi L, Hata Y, Ezuka A, Nagase H, Yamada E, Ohkubo H, Higurashi T, Sekino Y, Koide T, Iida H, Hosono K, Nonaka T, Takahashi H, Inamori M, Maeda S, Nakajima A
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Journal Title
Dig Endosc
Volume: 25(4)
Pages: 412-20
Peer Reviewed
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[Presentation] Capsule endoscopic findings of ulcerative colitis patients2012
Author(s)
Takuma Higurashi, Hiroki Endo, Masato Yoneda, Kunihiro Hosono, Eiji Sakai, Hirokazu Takahashi, Masahiko Inamori, Shiori Uchiyama, Takuto Kojima, Kenichi Kawana, Yutaka Natsumeda, Hajime Nagase, Atsushi Nakajima
Organizer
Digestive Disease Week 2012 Upper GI - Small Bowel Imaging Poster Session
Place of Presentation
Sandiego
Year and Date
2012-05-19
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