2014 Fiscal Year Final Research Report
Establishment of the comprehensive assay of myasthenica gravis-related autoantibody using bioluminescence
| Project/Area Number |
24790904
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurology
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| Research Institution | Nagasaki University (2013-2014)
Nagasaki Kawatana Medical Center (2012) |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HIGUCHI Osamu 国立病院機構長崎川棚医療センター, 臨床研究部, 研究員 (50361720)
MOTOMURA Masakatsu 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 (70244093)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 重症筋無力症 / アセチルコリン受容体抗体 / MuSK抗体 |
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| Outline of Final Research Achievements |
We planned the establishment of myasthenia gravis-related antibody using Gaussia luciferase lmmunoprecipitation (GLIP), different from the conventional RIA method.MuSK antibody assay was successful as well as the conventional method, however, we could not detect AChR antibody sufficiently.We also set up cell-based assay in corporation with University of Oxford.
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| Free Research Field |
神経内科学
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