2013 Fiscal Year Final Research Report
Effects of hypothalamo-pituitary damages on female reproductive functions.
| Project/Area Number |
24790946
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Endocrinology
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| Research Institution | Okayama University |
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Principal Investigator |
NAKAMURA Eri 岡山大学, 大学病院, 医員 (30612634)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 生殖内分泌 / 卵巣 / 下垂体 |
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| Research Abstract |
Ovarian steroidogenesis and folliculogenesis are controlled by pituitary gonadotropins and their receptors expressed in the ovary. In the patients with hypothalamo-pituitary disorders, impairment of reproductive functions often occurs. In that mechanism, not only the reduction of gonadotropins, but also the changes in growth hormone and prolactin, could be involved. In the present study, we investigated the biological impact of pituitary damages on the reproductive functions.
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[Journal Article] Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells2013
Author(s)
Terasaka T, Otsuka F, Tsukamoto N, Nakamura E, Inagaki K, Toma K, Ogura- Ochi K, Glidewell-Kenney C, Lawson MA, Makino H
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Journal Title
Mol Cell Endocrinol
Volume: 381
Pages: 8-15
DOI
Peer Reviewed
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