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2015 Fiscal Year Final Research Report

The analisis of serum cytokine and transcription factor level on the pathophysiology of late-onset circulatory collapse of extremely low birth infant

Research Project

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Project/Area Number 24791119
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Embryonic/Neonatal medicine
Research InstitutionJichi Medical University

Principal Investigator

MATANO MIYUKI  自治医科大学, 医学部, 助教 (90458315)

Project Period (FY) 2012-04-01 – 2016-03-31
Keywords晩期循環不全 / サイトカイン / 転写因子
Outline of Final Research Achievements

We analyzed cytokine and transcription factor levels in peripheral blood from 6 extremely low birth weight(ELBW) infants with late-onset circulatory collapse and those from 11 ELBW without late-onset circulatory collapse.
We found that inflammatory cytokines (IL-8,TNF-α) wear at hiher level in the late-onset circulatory collapse group.In these group, Serum level of IL-8 and TNF-α decreased over time.NT-proBNP was higher level in the both group.But we can not find significant differences between bith group.

Free Research Field

医歯薬学

URL: 

Published: 2017-05-10  

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