Effects of oxytocin administration on anorexia nervosa -a near-infrared spectroscopy (NIRS) study-

2014 Fiscal Year Final Research Report

• Project/Area Number: 24791195
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Psychiatric science
• Research Institution: Gunma University
• Principal Investigator: TAKEI Yuichi 群馬大学, 医学部附属病院, 助教 (30455985)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: NIRS

Outline of Final Research Achievements

We hypothetised that the some of patients with Anorexia nervosa (AN) have combined autistic spectrum disorder, and investigated the brain function using near infrared spectroscopy (NIRS) during the face-to-face conversation task that reflect social function and the verbal fluency task that have been investigated in various psychiatric disorders.
The brain activation of AN patients during the conversation task was almost maintained compared to healthy subjects. On the other hand, we found that the brain activation in some cases of AN during the verbal fluency task indicated the bipolar disorder like pattern (delayed activation peak). Also, we found the depression like brain activation pattern (lowered brain activation) in one AN at the weight loss, and the lowered brain activation was increased with recovered body weight.

Free Research Field

精神医学