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2013 Fiscal Year Final Research Report

Genome cohort study of gene-environment interactions aim to identify biomarkers for peripartum depression

Research Project

  • PDF
Project/Area Number 24791210
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionNagoya University

Principal Investigator

KUNIMOTO Shohko  名古屋大学, 医学(系)研究科(研究院), 特任助教 (30350135)

Project Period (FY) 2012-04-01 – 2014-03-31
Keywords臨床精神分子遺伝学 / 産後うつ病 / DNAメチル化 / 遺伝環境相互作用
Research Abstract

Identification of biomarkers to understand for pathogenesis and pathophysiology of postpartum depression is urgent issue to develop therapeutic and preventive application. To address this issue, we analyzed blood samples from peripartum women using endocrinologic or epigenetic approaches with respect to gene-environment interaction.

  • Research Products

    (9 results)

All 2014 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (3 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Common variants in bcl9 gene and schizophrenia in a Japanese population : association study, meta-analysis and cognitive function analysis2013

    • Author(s)
      Shiino T, Koide T, Kushima I, Ikeda M, Kunimoto S, Nakamura Y, Yoshimi A, Aleksic B, Banno M, Kikuchi T, Kohmura K, Adachi Y, Kawano N, Okada T, Inada T, jike4 H, Iidaka T, Suzuki M, Iwata N, Ozaki N
    • Journal Title

      Journal of Medical Biochemistry

      Volume: 32 Pages: 351-357

    • DOI

      10.2478/jomb-2013-0049

    • Peer Reviewed
  • [Journal Article] Definition and refinement of the 7q36.3 duplication region associated with schizophrenia2013

    • Author(s)
      Aleksic B, Kushima I, Ohye T, Ikeda M, Kunimoto S, Nakamura Y, Yoshimi A, Iritani S, Kurahashi H, Iwata N, Ozaki N
    • Journal Title

      Scientific Reports

      Volume: 3 Pages: 2587

    • DOI

      10.1038/srep02587

    • Peer Reviewed
  • [Journal Article] Differential effects of diazepam, tandospirone, and paroxetine on plasma brain-derived neurotrophic factor level under mental stress. Human Psychopharmacology2012

    • Author(s)
      Tamaji A, Iwamoto K, Kawamura Y, Takahashi M, Ebe K, Kawano N, Kunimoto S, Aleksic B, Noda Y, Ozaki N
    • Journal Title

      Clinical and Experimental

      Volume: 27 Pages: 329-333

    • DOI

      10.1002/hup.2220

    • Peer Reviewed
  • [Presentation] 認知機能におけるグリア型グルタミン酸トランスポーター(GLAST)の役割The role of glial glutamate transporter (GLAST) in cognitive functions in mice2014

    • Author(s)
      野田幸裕, 長谷川章, 谷口将之, 肥田裕丈, 毛利彰宏, 國本正子, 山田清文, 尾崎紀夫, 田中光一, 鍋島俊隆
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      東北大学百周年記念会館川内萩ホール, 仙台国際センター(仙台市)
    • Year and Date
      20140319-0321
  • [Presentation] 変異型Notch3 ノックインマウスの生化学的解析2012

    • Author(s)
      渡邉淳, 國本正子, 高橋慶吉
    • Organizer
      第31回 日本認知症学会学術集会
    • Place of Presentation
      つくば国際会議場(つくば市)
    • Year and Date
      20121026-28
  • [Presentation] 妊産婦の気分変動と血中ストレス関連物質との関連についての検討The examination of the relationships between postpartum blues and serum cortisol and cytokine levels2012

    • Author(s)
      玉地亜衣, 國本正子, 久保田智香, 水野妙子, 後藤節子, 村瀬聡美, 金井篤子, 尾崎紀夫
    • Organizer
      第34回日本生物学的精神医学会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      20120928-30
  • [Book] うつ病発症と遺伝子/環境相互作用2013

    • Author(s)
      松本友里恵, 國本正子, 尾崎紀夫
    • Total Pages
      5-13
    • Publisher
      精神保健研究
  • [Book] 妊産婦に生じるうつ病を対象としたゲノムコホート研究, 日本生物学的精神医学会誌2012

    • Author(s)
      中村由嘉子, 國本正子, 尾崎紀夫
    • Total Pages
      205-210
  • [Remarks] 國本正子, 中村由嘉子, 久保田智香, 尾崎紀夫. 産褥期精神障害. 脳科学辞典2012

    • URL

      http://bsd.neuroinf.jp/wiki/産褥期精神障害

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Published: 2015-06-25  

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