2013 Fiscal Year Final Research Report
Development of the real-time four-dimensional cone beam CT reconstruction technique for interactive radiotherapy
Project/Area Number |
24791261
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Radiation science
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Research Institution | Hokkaido University |
Principal Investigator |
TAKAO Seishin 北海道大学, 医学(系)研究科(研究院), 助教 (10614216)
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Project Period (FY) |
2012-04-01 – 2014-03-31
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Keywords | 放射線治療 / コーンビームCT / 四次元再構成 |
Research Abstract |
We have proposed a novel method for four-dimensional (4D) cone-beam computed tomography (CBCT) reconstruction with real-time tumor tracking technique. In the real-time tumor tracking, a fiducial marker inserted near the tumor is detected in the orthogonal fluoroscopic images. The three-dimensional position of the marker is calculated every 33 msec with an accuracy of 1 mm. According to the position of the marker, projection images can be classified into some phases. Four dimensional CBCT reconstruction is therefore available in each phase. Feasibility of the 4D CBCT reconstruction was evaluated through the experience using the testing machine, which has the same imaging devices in the proton therapy system in Hokkaido University Hospital. Additionally, characteristics of intrafractional baseline shift of tumor motion were analyzed to investigate efficacy of the 4D CBCT reconstruction method. Through the study, the feasibility and efficacy of the 4D CBCT reconstruction was confirmed.
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[Journal Article] Integration of a real-time tumor monitoring system into gated proton spot-scanning beam therapy : an initial phantom study using patient tumor trajectory data2013
Author(s)
Matsuura T, Miyamoto N, Shimizu S, Fujii Y, Umezawa M, Takao S, Nihongi H, Toramatsu C, Sutherland K, Suzuki R, Ishikawa M, Kinoshita R, Maeda K, Umegaki K, and Shirato H
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Journal Title
Med Phys
Volume: 40(7)
Pages: 071729
Peer Reviewed
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[Presentation] Development and Commissioning of the Spot Scanning Proton Beam Therapy System2014
Author(s)
Takao S, Toramatsu C, Matsuura T, Nihongi H, Yamada T, Miyamoto N, Shimizu S, Hashimoto T, Onimaru R, Kinoshita R, Onodera S, Umegaki K, and Shirato H
Organizer
1st GI-CoRE Medical Science and Engineering Symposium
Place of Presentation
Sapporo
Year and Date
2014-02-23
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[Patent(Industrial Property Rights)] 放射線治療システム2013
Inventor(s)
清水伸一, 高尾聖心, 宮本直樹, 松浦妙子, 梅川徹, 平本和夫, 馬場理香, 佐々木淑江, 長峯嘉彦
Industrial Property Rights Holder
北海道大学, 株式会社日立製作所
Industrial Property Rights Type
特許権
Industrial Property Number
特願2013-162656
Filing Date
2013-08-05