Clinical application of the four-dimensional radiation treatment planning

2014 Fiscal Year Final Research Report

• Project/Area Number: 24791295
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: MIYABE Yuki 京都大学, 医学(系)研究科(研究院), 講師 (60522505)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 放射線治療 / 4次元治療計画 / 呼吸性移動 / 非剛体レジストレーション / Deformable registration

Outline of Final Research Achievements

Accuracy of respiratory motion management in radiotherapy treatment planning was investigated. Clinical data of patients undergoing stereotactic body radiotherapy was analyzed, and the largest positional error (maximum 9.9 mm) was observed in deformable image registration(DIR). The DIR is a fundamental task in 4D dose calculation. It provides soft tissue alignment between different image sets where the organ motion exists. The results of this study indicated that DIR performance on each patient should be assessed. For clinical application of 4D treatment planning, a quality assurance tool designed to check the DIR accuracy easily was developed.

Free Research Field

医学物理