2013 Fiscal Year Final Research Report
Evaluation of NF-kappaB as a marker of radioresistance in Glioblastoma
Project/Area Number |
24791305
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Radiation science
|
Research Institution | Kobe University |
Principal Investigator |
NOR SHAZRINA 神戸大学, 医学部附属病院, 医員 (30610737)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Keywords | 放射線科学 / 放射線腫瘍学 / 放射線抵抗性 / 放射線治療 |
Research Abstract |
We previously reported in a clinical setting that NF-kappaB may be a novel marker for radioresistance. The aim of this study was to evaluate NF-kappaB as a marker of radioresistance in refractory tumors such as glioblastoma and others. Immunohistochemistry was performed using pretreatment biopsy specimen to evaluate the presence of NF-kappaB expression in these tumors. Similar experiments was performed in subgroups of recurrent tumor specimens. The prognostic value of other molecular markers such as EGFR and bcl-2 were also evaluated and compared with NF-kappaB's.
|
Research Products
(14 results)
-
-
-
[Presentation] A novel radiosensitizer, monogalactosyl diacylglycerol, enhanced the cytotoxic effects for the pancreatic cancer2014
Author(s)
H Akasaka, R Sasaki, I Takayama, M Nakahana, NS Sulaiman, D Miyawaki, K Yoshida, Y Ejima, H Uezono, Y Mizushina
Organizer
33rd European Society for Radiotherapy and Oncology Congress
Place of Presentation
Vienna, Austria
Year and Date
2014-04-04
-
[Presentation] 小児Glioma に対する放射線治療の経験2013
Author(s)
松尾圭朗, 吉田賢史, 宮脇大輔, 上薗 玄, 江島泰生, ノルシャズリナ, 松本葉子, 篠山隆司, 早川晶, 佐々木良平
Organizer
日本放射線腫瘍学会第26回学術大会
Place of Presentation
青森, 日本
Year and Date
2013-10-18
-
-
-
-
[Presentation] A novel radiosensitizer of the functional food component, monogalactosyl diacylglycerol (MGDG) from spinach, enhanced the cytotoxic effects for the pancreatic cancer in vitro and in vivo2013
Author(s)
H Akasaka, R Sasaki, N Mukumoto, M Nakayama, NS Sulaiman, D Miyawaki, K Yoshida, Y Ejima, Y Mizushina
Organizer
American Society for Radiation Oncology 55th Annual Meeting
Place of Presentation
Georgia, USA
Year and Date
2013-09-22
-
[Presentation] Impact of symptom rescue by fractionated radiotherapy alone for rare angiogenetic neoplasm of the abdomen, vertebra, and head and neck regions2013
Author(s)
Y Matsuo, K Yoshida, D Miyawaki, Y Ejima, NS Sulaiman, Y Kojima, M Yamaguchi, K Sugimoto, R Sasaki
Organizer
American Society for Radiation Oncology 55th Annual Meeting
Place of Presentation
Georgia, USA
Year and Date
2013-09-22
-
[Presentation] Radiotherapy for low-grade glioma2013
Author(s)
NS Sulaiman, K Yoshida, H Nishimura, D Miyawaki, A Harada, O Muraoka, K Uehara, M Nakayama, T Sasayama, E Kohmura, R Sasaki
Organizer
The 72nd Annual Meeting of the Japan Radiological Society
Place of Presentation
Yokohama, Japan
Year and Date
2013-04-11
-
-
[Presentation] Clinical results of particle beam radiation therapy for lung metastases2012
Author(s)
NS Sulaiman, O Fujii, D Miyawaki, Y Demizu, Y Niwa, K Terashima, M Mima, R Sasaki, M Murakami, N Fuwa
Organizer
The 6th Takahashi Memorial Symposium & The Japan-US Cancer Therapy International Joint Symposium
Place of Presentation
Hiroshima, Japan
Year and Date
2012-07-19
-
[Presentation] 脳幹部Gliomaに対する放射線治療の経験2012
Author(s)
吉田賢史, 西村英輝, 宮脇大輔, 原田文, 村岡修, ノルシャズリナ, 上原和之, 早川晶, 篠山隆司, 佐々木良平
Organizer
第71回日本医学放射線学会総会
Place of Presentation
Yokohama, Japan
Year and Date
2012-04-12
-