2014 Fiscal Year Final Research Report
Development of tumor control probability model based on probability theory
| Project/Area Number |
24791334
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
|
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| Research Institution | Kitasato University |
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Principal Investigator |
|
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 前立腺癌 / 腫瘍制御モデル |
|---|
| Outline of Final Research Achievements |
Retrospective analysis of 305 prostate cancer patients treated by low-dose-rate brachytherapy with 66 months follow-up was published in paper. In addition retrospective analysis of 178 patients teated by high-dose rate brachytherapy was also published in another paper. Although we tried to find differences between these two dose-rate brachytherapy and to make a tumor control probability model (TCP) based on these data, there was no significant differences as these treatments had very low recurrence rates and it was difficult to make a reasonable TCP model.
We also tried to take a biological approach in addition to above mentioned clinical approach. Although we started to examine the relationship between radiation dose and DNA double-strand brake, there was no time to complete this examination untile the end of study period.
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| Free Research Field |
放射線腫瘍学
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