Study on early diagnosis and cost-effectiveness to the dementia patients using amyloid imaging

2014 Fiscal Year Final Research Report

• Project/Area Number: 24791363
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology (2013-2014); 独立行政法人国立精神・神経医療研究センター (2012)
• Principal Investigator: ITO KIMITERU 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (40602074)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 認知症 / PET / アミロイド

Outline of Final Research Achievements

The aim of this study was to evaluate the impact of amyloid positron emission tomography (PET) to diagnose elderly patients with dementia in daily practice. Amyloid PET showed positive findings in forty-eight out of eighty-five patients with cognitive disorders who were diagnosed by the clinical criteria of the National Institute on Aging-Alzheimer’s Association (NIA-AA). Our result suggested amyloid PET had clinical impacts on patients with Alzheimer`s disease and mild cognitive impairments who were diagnosed based on the clinical criteria alone. The diagnosis of dementia using amyloid PET may be helpful to change the pharmacological regimen of dementia patients. Our results suggest that amyloid PET contribute medical care economy.

Free Research Field

放射線医学