2013 Fiscal Year Final Research Report
Instruction of the insulin-producing cell by Direct Reprogramming
| Project/Area Number |
24791374
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General surgery
|
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| Research Institution | Osaka University |
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Principal Investigator |
|
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| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Keywords | ADSC / MafA / PDX-1 / Ngn3 / Direct Reprogramming / インスリン |
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| Research Abstract |
Direct reprogramming by introducing pancreatic transcription factors (MafA, PDX-1, Ngn3) into adipose tissue derived stem cell (ADSC) could not induce insulin-producing cell in vitro and in vivo (limited hepatic transplantation), in my study.
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