2014 Fiscal Year Final Research Report
Erectile dysfunction after pelvic surgery
| Project/Area Number |
24791632
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Urology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 勃起障害 / 骨盤内手術 |
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| Outline of Final Research Achievements |
We established an experimental rat model similar to the actual nerve-sparing radical prostatectomy (RP) in patients. A tissue sealing sheet has recently been used for intraoperative bleeding in RP. However, the efficacy of tissue sealing sheet for erectile function following nerve-sparing RP remains unclear. We evaluated the effect of the tissue sealing sheet on nerve injury-related erectile dysfunction (ED). The tissue sealing sheet attenuated ED following cavernous nerve dissection in a rat model of nerve-sparing RP. The tissue sealing sheet may thus represent a useful therapeutic approach to improve ED occurring after nerve-sparing RP, and the prospective clinical trial is on going to elucidate the effect of the tissue sealing sheet.
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| Free Research Field |
泌尿器科
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