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2014 Fiscal Year Final Research Report

Electrical stimulation with an implanted electrode for vocal fold adduction in unilateral paralyzed larynx

Research Project

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Project/Area Number 24791736
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Otorhinolaryngology
Research InstitutionAsahikawa Medical College

Principal Investigator

NOMURA Kenichiro  旭川医科大学, 医学部, 助教 (00466484)

Research Collaborator KATADA Akihiro  旭川医科大学, 医学部, 講師 (90281899)
Project Period (FY) 2012-04-01 – 2015-03-31
Keywords喉頭麻痺 / 機能的電気刺激
Outline of Final Research Achievements

The aim of this study was to create a suitable electrode, and to examine the feasibility of unilateral stimulation to produce vocal fold adduction in unilateral paralyzed larynx. Four canines were used in this study. An electrode array consisted of 8 active platinum disk electrodes, mounted on a silicone plate. This electrode array was implanted into thyroplasty window to stimulate thyroarytenoid (TA) muscle. First we examined two innervated canines and confirmed that this new created electrode array could produce appreciate glottal closure. Then RLNs were sectioned, or sectioned and repaired. In denervated group TA stimulation could produce nominal glottal closure with high current. On the other hand in reinnervated group TA stimulation could produce optimal glottal closure with low current. This study demonstrated that TA stimulation with new created electrode could produce optimal glottal closure. However, reinnervation was desired for optimal glottal closure.

Free Research Field

耳鼻咽喉科

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Published: 2016-06-03  

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