2013 Fiscal Year Final Research Report
Searching the drugs for recurrent corneal erosion by evaluating the corneal epithelial adhesion ability
| Project/Area Number |
24791857
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Yamaguchi University |
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Principal Investigator |
YAMADA Naoyuki 山口大学, 医学(系)研究科(研究院), 助教 (70437630)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 眼薬理学 |
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| Research Abstract |
We were able to build an evaluation model of the corneal epithelium adhesion ability using the laboratory animal.Measuring corneal epithelium adhesion ability with diabetes group and control group, it was 24.9+-13.4 g and 33.2+-18.9 g. But there was no significant difference between diabetes group and control group.If the experimental procedure is improved, we are able to know a quantitative evaluation of the corneal epithelium adhesion ability in in vivo. In addition, this system will be useful to develop the corneal epithelial wound healing eye drops.
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