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2013 Fiscal Year Final Research Report

The understanding of the neural circuits in the brainstem involved in jaw movement using laser photolysis

Research Project

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Project/Area Number 24791984
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Functional basic dentistry
Research InstitutionShowa University

Principal Investigator

NAKAMURA Shiro  昭和大学, 歯学部, 助教 (60384187)

Project Period (FY) 2012-04-01 – 2014-03-31
Keywords顎運動 / 三叉神経運動核 / プレモーターニューロン / ケージド化合物 / パッチクランプ / 脳幹スライス標本
Research Abstract

We revealed that the neural circuits involved in jaw movement differed between jaw-closing and jaw-opening muscles and changed with postnatal development, using the systematic laser photostimulation method. The outcomes of this study provide information of understandings of mechanisms that are responsible for development and maintenance of orofacial functions and physical-psychic activities. Furthermore, our basic data obtained from this study are important for development of treatments of masticatory disorders and rehabilitation of masticatory functions.

  • Research Products

    (12 results)

All 2014 2013 2012

All Journal Article (4 results) Presentation (8 results)

  • [Journal Article] Electrophysiological and morphological properties of rat supratrigeminal premotor neurons targeting the trigeminal motor nucleus2014

    • Author(s)
      Nakamura S, Nakayama K, Mochizuki A, Sato F, Haque T, Yoshida A, Inoue T
    • Journal Title

      J Neurophysiol

      Volume: 111(9) Pages: 1770-1782

  • [Journal Article] Postnatal changes in the repetitive firing properties of rat jaw-closing motoneurons2013

    • Author(s)
      Inoue T, Yamaoka A, Hironaka S, Nakamura S, Nakayama K, Mochizuki A, Mukai Y, Itabashi K
    • Journal Title

      J Jpn Soc Stomatognath Funct

      Volume: 19 (2) Pages: 137-144

  • [Journal Article] Coordination of NMDA-induced rhythmic activity in the trigeminal and hypoglossal nerves of neonatal mice in vitro2013

    • Author(s)
      Ihara Y, Nakayama K, Nakamura S, Mochizuki A, Takahashi K, Inoue T
    • Journal Title

      Neurosci Res

      Volume: 75(2) Pages: 138-149

  • [Journal Article] Convergent premotoneuronal inputs to single trigeminal motoneurons2012

    • Author(s)
      Nonaka M, Nishimura A, Nakamura S, Nakayama K, Mochizuki A, Iijima T, Inoue T
    • Journal Title

      J Dent Res

      Volume: 91 Pages: 888-893

  • [Presentation] Neural mechanisms controlling jaw and tongue movements. Symposia2013

    • Author(s)
      Inoue T, Nonaka M, Ihara Y, Nakamura S, Nakayama K, Yazawa I, Mochizuki A
    • Organizer
      Neural control of feeding behaviors
    • Place of Presentation
      Kyoto
    • Year and Date
      20130620-23
  • [Presentation] Effects of histamine on neurotransmission from the mesencephalic trigeminal nucleus to trigeminal motoneurons in rats2013

    • Author(s)
      Gemba C, Nakayama K, Nakamura S, Mochizuki A, Inoue M, Inoue T
    • Organizer
      Society for Neuroscience 43rd annual meeting
    • Place of Presentation
      San Diego
    • Year and Date
      2013-11-13
  • [Presentation] 三叉神経上核プレモーターニューロンの形態学的および生理学的特性2013

    • Author(s)
      中村史朗, 中山希世美, 望月文子, 吉田篤, 井上富雄
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Year and Date
      2013-09-21
  • [Presentation] Postnatal development of convergent premotoneuronal inputs to single trigeminal motoneurons2013

    • Author(s)
      Nakamura S, Matsuda K, Nonaka M, Mochizuki A, Nakayama K, Iijima T, Yokoyama A, Inoue T
    • Organizer
      2nd Meeting of the International Association for Dental Research
    • Place of Presentation
      Asia Pacific Region, Bangkok
    • Year and Date
      2013-08-21
  • [Presentation] Convergent inputs to single trigeminal motoneurons from the premotor neurons which were located in the regions surrounding the trigeminal motor nucleus in rats2012

    • Author(s)
      Nakamura S, Nonaka M, Matsuda K, Nakayama K, Mochizuki A, Iijima T, Inoue T
    • Organizer
      NANOSYMPOSIUM; Oral movements; Theme D: Sensory and Motor Systems, Soc Neurosci abstr 14.10, Neuroscience
    • Place of Presentation
      New Orleans
    • Year and Date
      20121010-13
  • [Presentation] Coordination of NMDA-induced suckling-like rhythmic activity in the trigeminal and hypoglossal nerves of In vitro brain preparations from newborn mice2012

    • Author(s)
      Inoue T, Nakayama K, Ihara Y, Nakamura S, Mochizuki A, Takahashi K
    • Organizer
      NANOSYMPOSIUM; Oral movements; Theme D: Sensory and Motor Systems, Soc Neurosci abstr 14.01, Neuroscience 2012
    • Place of Presentation
      New Orleans
    • Year and Date
      20121010-13
  • [Presentation] 三叉神経運動ニューロン樹状突起における情報処理機構2012

    • Author(s)
      中村史朗, 望月文子, 中山希世美, 井上富雄
    • Organizer
      日本顎口腔機能学会第49回学術大会
    • Place of Presentation
      北九州
    • Year and Date
      2012-10-21
  • [Presentation] 三叉神経運動核周囲領域からの三叉神経運動ニューロンに対する収束性入力2012

    • Author(s)
      野中睦美, 松田啓資, 中村史朗, 中山希世美, 望月文子, 横山敦郎, 飯島毅彦, 井上富雄
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      郡山
    • Year and Date
      2012-09-15

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Published: 2015-06-25  

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