2013 Fiscal Year Final Research Report
The effects of gene associated with sucrose phosphotransferase system on biofilm formation of Streptococcus mutans
| Project/Area Number |
24792027
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Conservative dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
KIMURA Tomoko 徳島大学, ヘルスバイオサイエンス研究部, 助教 (20581367)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 歯学 / う蝕 / 細菌 / 遺伝子 / バイオフィルム |
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| Research Abstract |
The aim of this study was to investigate the involvement of scrA gene deeply related to the acidogenic activity in cariogenic bacterium in the initial adhesion and glucan synthesis by Streptococcus mutans. ELISA assay revealed that scrA gene had an effect on the initial adhesion.
The measurement of glucan demonstrated that scrA gene involved in the synthesis of glucan, a component of biofilm.
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