Investigation of biological pathogenesis and development of prevention diagnosis protocol of peri-implantitis.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24792083
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthetic dentistry
• Research Institution: Okayama University
• Principal Investigator: MINO Takuya 岡山大学, 医歯(薬)学総合研究科, 助教 (10625718)
• Research Collaborator: KUBOKI Takuo ; SONOYAMA Wataru ; ONO Mitsuaki ; ONO Aya
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 口腔インプラント / インプラント周囲炎 / 生物学的リスクファクター / 次世代シークエンサー / 診断プロトコル

Outline of Final Research Achievements

The purpose of this study was to identify the biological markers that are involved in the onset and progression of peri-implantitis. First, we developed a clinical examination protocol by referring to the previous reports and investigated the prospective study for the initial peri-implantitis patient using the developed protocol. The subject of this study was five and, basic information of subjects was shown below, average age: 71.0 ± 4.6 years, average number of implants per patient : 4.8 ± 2.4, average number of implant with peri-implantitis：1.4 ± 0.5) . To identify the biological markers, gingival crevicular fluids around the oral implant and natural tooth were collected by using the paper points. ,The adequate amount of bacterial DNA could be collected for 16S rRNA sequencing using this protocol.

Free Research Field

歯科補綴学