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2014 Fiscal Year Final Research Report

Effect of dietary environment in weaning period on feeding behavior and functional development

Research Project

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Project/Area Number 24792304
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Orthodontic/Pediatric dentistry
Research InstitutionShowa University

Principal Investigator

OOKA Takafumi  昭和大学, 歯学部, 講師 (30453632)

Project Period (FY) 2012-04-01 – 2015-03-31
Keywords自閉症 / 疾患モデルラット / 摂食行動 / 離乳期
Outline of Final Research Achievements

This study aimed to identify the change and process of these characteristics in childhood, hence, the feeding behavior of autism-model rat pups were examined through the weaning period (from 11th postnatal day to 25th). As a result, the number of contacts and the average number of meals ingested together of the two autism-model rats group showed lower numbers significantly compared with the group of healthy rats. In addition, we measured the amount of food intake in daytime and night-time. The results showed that the amount of food intake of night-time in the group of healthy rats significantly greater than the amount of daytime. However, there was no significant difference between the amount of food intake of daytime and night-time in the group of autism-model rat pups. These findings indicate that the rat pup models of autism displayed some characteristic feeding behaviors and the circadian variation in feeding behaviour could be different between the autism-model rats.

Free Research Field

摂食嚥下リハビリテーション

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Published: 2016-06-03  

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