2013 Fiscal Year Final Research Report
The functional significance of the olivo-cerebellar input in obstacle avoidance during locomotion.
| Project/Area Number |
24800018
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Physical education
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SATO Yamato 東京大学, 総合文化研究科, 助教 (40637914)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Keywords | 下オリーブ核－登上線維系 / 障害物回避 / 小脳 / ラット / 筋電図 |
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| Research Abstract |
The purpose of this study was to investigate the effect of lesions to the olivo-cerebellar pathway on obstacle avoidance during locomotion. The results are as follows. 1) The post-lesion animals showed excessive toe elevation, shortening stride length and hyper flexion of knee and ankle joints during the swing phase. 2) In post-lesion animals at normal ground locomotion, the vastus lateralis did not show muscle activity during the late swing phase. The biceps femoris showed muscle activity at lift-off. Moreover, the gastrocnemius showed prolongation of quiescent and active period during the stance phase and late swing phase, respectively. 3) In obstacle avoidance during locomotion, the post-lesion animals showed fluctuating toe trajectory. In this case, some muscle (the vastus lateralis, the biceps femoris, the tibialis anterior and the gastrocnemius) of avoiding limb showed different activity from pre-lesion animals.
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