2013 Fiscal Year Final Research Report
Effect of moderate-intensity exercise and heat stimulation on inactivity-induced insulin resistance
| Project/Area Number |
24800079
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied health science
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| Research Institution | Nagaoka National College of Technology |
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Principal Investigator |
KAWAMOTO EMI 長岡工業高等専門学校, その他部局等, 助教 (40634514)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Keywords | 不活動 / インスリン抵抗性 / 骨格筋 / 軽運動 / 温熱処置 |
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| Research Abstract |
Chronic muscle disuse - produced by the condition of physical inactivity induced insulin resistance in human skeletal muscle. I studied whether moderate-intensity exercise and heat stimulation that led to a significant amplification in phosphorylation of AMP-activated protein kinase (AMPK), prevented insulin resistance that induced in postural muscle by hindlimb immobilization. As a result, our study suggested that it was necessary to activate AMPK to a sufficiently level for preventing inactivity-induced insulin resistance.
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