2013 Fiscal Year Final Research Report
Characterization of condensin-mediated DNA damage response in plants
| Project/Area Number |
24870026
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Plant molecular biology/Plant physiology
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
SAKAMOTO Takuya 東京理科大学, 理工学部, ポストドクトラル研究員 (40637691)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Keywords | シロイヌナズナ / コンデンシンII / 染色体配置 |
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| Research Abstract |
A plant chromosomal protein complex, condensin II, is known to function in alleviating DNA damage. However, it is still unclear that how condensin II acts in DNA damage response. To reveal the detailed function of condensin II in the alleviation of DNA damage, we characterized Arabidopsis condensin II mutants. As a result, it was found that Arabidopsis condensin II is unlikely to be required for the DNA damage repair but functions in the high compaction of genome-wide chromatin. These findings indicate that Arabidopsis condensin II is considered to physically protect DNA through the high compaction of chromatin.
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