2013 Fiscal Year Final Research Report
Analysis of the toxicity of illegal harbals with approach of pharmacokinetics and toxicology
| Project/Area Number |
24890088
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Legal medicine
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| Research Institution | Mie University |
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Principal Investigator |
IKEMURA Mayumi 三重大学, 医学(系)研究科(研究院), 助教 (30515490)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Keywords | 合法ハーブ / 薬物動態 / 乱用薬物 / ＪＷＨ－２０３ / ＭＰＨＰ |
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| Research Abstract |
In this study, we analyze the component of illegal harbals and investigate the correlation among the respiratory intake of illegal harbals, blood concentration and toxicity. We detected the regulated compound,"JWH-203", from the illegal harbals obtained in our laboratory, suggesting that the illegal harbals should contain the regulated compounds. It is suggested that the pharmacokinetics and toxicity of illegal harbals may differ depending on the variety, whereas the component of illegal harbals may not be detected in blood with lethal doses.
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