2013 Fiscal Year Final Research Report
Analysis of strengthening human dentin after UV irradiation
| Project/Area Number |
24890119
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Conservative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
FURUYA Yu 大阪大学, 歯学部附属病院, 医員 (20635411)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Keywords | 紫外線 / 象牙質 / コラーゲン / 核磁気共鳴法 |
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| Research Abstract |
The results of NMR showed several peaks at 26, 62 and 170 ppm in the NMR spectrum shifted after UV irradiation. The shifts at 26, and 62 ppm suggested changes in fundermental structures including CH2. The changes at 26 and 62 ppm were clear under the condition with water. These results suggest that water may play an important role in accelerating molecular structural changes in collagen after UV irradiation and inter-molecular bond associated with water was produced at CH2chain after UV irradiation with water. The change at 170 ppm suggested that the C=O bond in proline converted into a hydrogen bondor an inter-molecular bond associated with water.
Structural changes in C=O and CH2 of type I collagen may be one of the reasons for strengthening human dentin after UV irradiation.
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