2013 Fiscal Year Final Research Report

Analysis and identification of early diagnostic markers of metastasis in oral cancer

Research Project

Project/Area Number	24890175
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Surgical dentistry
Research Institution	Kumamoto University
Principal Investigator	TANAKA TAKUYA 熊本大学, 医学部附属病院, 非常勤診療医師 (30631767)
Project Period (FY)	2012-08-31 – 2014-03-31
Keywords	臨床腫瘍学
Research Abstract	Oral Squamous Cell Carcinoma (OSCC) is in serious disease patient quality of life and life-threatening. In the treatment of oral Squamous Cell Carcinoma (OSCC), operative therapy and chemotherapy-radiation x-ray, and greatly contributed to improve the survival rate of patients with cancer and recurrences. But distant metastasis suppressor is difficult in the current development of a new treatment is desired. Applicant transplant, oral Squamous Cell Carcinoma (OSCC) cell line in nude mice and the successful establishment of the and create a model from a high metastatic spread to the lung. And micro-array analysis, discovery and identification as a candidate gene admitted Angptl4 (angiopoietin-like protein 4) upswing.