2013 Fiscal Year Final Research Report

Referred pain in the oral and maxillofacial area occurs in heart disease

Research Project

Project/Area Number	24890262
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Surgical dentistry
Research Institution	The Nippon Dental University
Principal Investigator	IDE Ryoji 日本歯科大学, 生命歯学部, 助教 (10638084)
Project Period (FY)	2012-08-31 – 2014-03-31
Keywords	関連痛 / 心疾患 / TRPV1 / ナトリウムチャネル / 篩状神経節
Research Abstract	Firstly, we developed a procedure and became able to obtain a steadily number of neurons from acutely isolated and cultured immature rat nodose ganglion (NG). Next, using electrophysiological technique, we targeted small NG neurons possessed tetrodotoxin resistant (TTX-R) voltage-gated sodium channels and investigated whether excitement occurs at acutely applied capsaicin on the neurons. The results showed that action potential could be induced by the capsaicin treatment in 72% of the neurons. We examined.

(3 results)