Innovative electrochemical imaging device for bioanalysis

2015 Fiscal Year Final Research Report

• Project/Area Number: 25248032
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Analytical chemistry
• Research Institution: Tohoku University
• Principal Investigator: Matsue Tomokazu 東北大学, 原子分子材料科学高等研究機構, 教授 (70173797)
• Co-Investigator(Kenkyū-buntansha): INO KOSUKE 東北大学, 大学院環境科学研究科, 助教 (00509739) ; TAKAHASHI YASUFUMI 東北大学, 原子分子材料科学高等研究機構, 助教 (90624841) ; RAMON JAVIER 東北大学, 原子分子材料科学高等研究機構, 助教 (50613270) ; SHIKU HITOSHI 東北大学, 大学院環境科学研究科, 准教授 (10361164) ; INOUE KUMI 東北大学, 大学院環境科学研究科, 講師 (20597249)
• Project Period (FY): 2013-05-31 – 2016-03-31
• Keywords: 電気化学イメージング / バイオ分析 / バイオMEMS / 生体分子 / マイクロ・ナノ化学 / 細胞機能解析 / 微小電極アレイ

Outline of Final Research Achievements

In the present study, we have developed two-types of electrochemical devices for bioimaging. One was a bio-LSI device which was based on large-scale integrated (LSI) circuits dedicated to bioanalysis. The other was a local redox cycling-based electrochemical (LRC-EC) device utilizing local redox cycling. The device consisted of many switching sensors incorporated into a small chip device to detect electrochemical responses. These bioimaging devices were successfully applied for evaluation of oxygen consumption and secreted chemicals from cells, and cell differentiation.

Free Research Field

電気化学