Research on the measurement technology of breast tumor angiogenesis

2017 Fiscal Year Final Research Report

• Project/Area Number: 25249050
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Electron device/Electronic equipment
• Research Institution: Hiroshima University
• Principal Investigator: Kikkawa Takamaro 広島大学, ナノデバイス・バイオ融合科学研究所, 特任教授 (60304458)
• Co-Investigator(Kenkyū-buntansha): 小出 哲士 広島大学, ナノデバイス・バイオ融合科学研究所, 准教授 (30243596) ; 有廣 光司 広島大学, 病院(医), 教授 (70232064) ; 黒木 伸一郎 広島大学, ナノデバイス・バイオ融合科学研究所, 准教授 (70400281)
• Project Period (FY): 2013-04-01 – 2018-03-31
• Keywords: 乳腺腫瘍 / 血管新生 / 複素誘電率 / 免疫染色 / 乳がん / 計測システム / CMOS / 回路

Outline of Final Research Achievements

A measurement technology for the distribution of angiogenesis, which is spread by metastasis or infiltration of a malignant tumor, was developed with respect to pathology and electromagnetism. In particular, the angiogenesis distributions in the excised breast tumor tissues from patients were measured at the histopathology suite. A measurement system for the complex impedance of the malignant tumor angiogenesis region was developed and the complex permittivity was measured. The correlation between the complex permittivity and the volume fraction of the cancer cells was measured. The CMOS circuits for the measurement system by the use of impulse electromagnetic waves were developed for the measurement of the distribution of angiogenesis.

Free Research Field

電子工学