2017 Fiscal Year Final Research Report
Characterization of mechanisms for coordinated proliferation of the eukaryotic host cell and the chloroplast
| Project/Area Number |
25251039
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Evolutionary biology
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| Research Institution | National Institute of Genetics |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2018-03-31
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| Keywords | 細胞内共生 / 葉緑体分裂 |
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| Outline of Final Research Achievements |
We aimed to understand the mechanism for coordinated proliferation of the eukaryotic host cell and the chloroplast which played a pivotal role in endosymbiotic establishment of the chloroplast. By characterizing eukaryotic algae, we found (1) that the division of chloroplast of both primary and secondary endosymbiotic origin is restricted to S phase by S-phase-specific expression of nucleus-encoded chloroplast division genes/proteins, (2) that initiation of chloroplast division site constriction is required for the host cell cycle progression, and (3) that the host cell cycle progression is restricted to night when photosynthesis does not operate to avoid photosynthetic oxidative stress. These results suggest that the division synchronization of the host cell and the chloroplast is enabled by interactive restrictions between the host cell and the chloroplast.
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| Free Research Field |
進化細胞生物学
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