2015 Fiscal Year Final Research Report
Molecular elucidation of sensory-dependent control of bone metabolism and its clinical application
Project/Area Number |
25253090
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Research Category |
Grant-in-Aid for Scientific Research (A)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Orthopaedic surgery
|
Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
TAKEDA Shu 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (30376727)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Keywords | 骨代謝学 |
Outline of Final Research Achievements |
We demonstrated that Sema3A, a prototype of chemo-repellent, regulates sensory innervation into bone tissue, which in turn orchestrates the normal bone remodeling and sensory nerves are essential for normal bone regeneration.
|
Free Research Field |
骨代謝学・分子生物学
|