2015 Fiscal Year Final Research Report
Optical control of cellular functions by PCDR technology
| Project/Area Number |
25282232
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomolecular chemistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE KAZUNORI 岡山大学, 大学院自然科学研究科, 助教 (70602027)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 核酸 / RNA / 光誘導 / 翻訳 / 細胞分化 |
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| Outline of Final Research Achievements |
In this study, methods to control cellular functions by visible and infrared light were developed based on “Photoinduced Cytosolic Dispersion of RNA (PCDR) technology” for introducing RNAs into cytoplasm only within irradiated cells. Optimization of PCDR using infrared light, temporal control of introduction of two kinds of RNAs, the application to speroid (three-dimensional multicell model), and optical control of the cell functions have been archived.
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| Free Research Field |
生体分子工学
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