2015 Fiscal Year Final Research Report
Analysis of time constant encoded in circadian clock proteins
| Project/Area Number |
25291039
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biophysics
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| Research Institution | Institute for Molecular Science |
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Principal Investigator |
AKIYAMA Shuji 分子科学研究所, 協奏分子システム研究センター, 教授 (50391842)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 概日時計 |
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| Outline of Final Research Achievements |
This research project aims at analyzing pre-steady-state relaxations of the ATPase activity of a clock protein, KaiC, which is known to be a pacemaker of the circadian clock system in cyanobacteria. A fine correlation between the relaxation time of KaiC alone and the clock-system’s frequency supports the idea that the slow ATPase in KaiC yields the circadian response frequency of intermolecular interactions with other clock-related proteins.
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| Free Research Field |
生物物理学
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