2016 Fiscal Year Final Research Report
Exploring the whole mechanisms of adipocytokine regulation of atherosclerosis
| Project/Area Number |
25292175
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Veterinary medical science
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 循環器 / 病態 |
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| Outline of Final Research Achievements |
In this project, we aimed to explore the mechanisms of actions of adipocyte-derived cytokine (adipocytokine), which is recognized as one of the possible mediators responsible for the visceral obesity-induced cardiovascular diseases including atherosclerosis. We have clarified the novel cardiovascular effects and mechanisms exerted by adipocytokines. We also succeeded in classifying adipocytokines into good and bad type. Based on the present findings and further investigations, it is expected that adipocytokines might be applicable to the diagnosis, prevention and treatment for metabolic cardiovascular diseases.
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| Free Research Field |
循環薬理学
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