Elucidation of regulatory mechanism of neurovascular coupling interaction in retinal circulation and clinical application for early diagnosis of diabetic retinopathy

2016 Fiscal Year Final Research Report

• Project/Area Number: 25293352
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Asahikawa Medical College
• Principal Investigator: NAGAOKA Taiji 旭川医科大学, 医学部, 准教授 (00333691)
• Co-Investigator(Kenkyū-buntansha): 横田 陽匡 旭川医科大学, 医学部, 助教 (60431417) ; 大谷 真一 旭川医科大学, 大学病院, その他 (70548841) ; 高橋 淳士 旭川医科大学, 医学部, 助教 (90422047) ; 善岡 尊文 旭川医科大学, 大学病院, その他 (20548854)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 網膜微小循環 / 糖尿病網膜症 / 神経－血管連関

Outline of Final Research Achievements

We have revealed that 1) retinal glial cells may be involved with the retinal neurovascular coupling during systemic hyperoxia 2) EDHF may be involved with histamine-induced vasodilation in retinal porcine arterioles 3) habitual smoking may have some influences on retinal circulation in patients with diabetic retinopathy.

Free Research Field

眼科学