2015 Fiscal Year Final Research Report
Effects of catecholamine on gut immune systems.
Project/Area Number |
25293367
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Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Emergency medicine
|
Research Institution | Keio University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
SUZUKI Takeshi 慶應義塾大学, 医学部, 講師 (80327600)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Keywords | カテコラミン / 敗血症 / 腸内細菌 / 腸管免疫機構 |
Outline of Final Research Achievements |
Although the present study demonstrated that high concentoration of norepinephrine stimulated bacterial proliferation of Escherichia coli and Staphylococcus epidermidis from clinical specimen, the concentrations of catecholamine in gut lumen were relatively low in sepsis. These datas suggest that endgenous catecholamine has little effects to modify intestinal badterial flora and gut immune systems.
|
Free Research Field |
麻酔学・集中治療医学
|