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2015 Fiscal Year Final Research Report

Effects of catecholamine on gut immune systems.

Research Project

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Project/Area Number 25293367
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Emergency medicine
Research InstitutionKeio University

Principal Investigator

MORISAKI Hiroshi  慶應義塾大学, 医学部, 教授 (60182226)

Co-Investigator(Kenkyū-buntansha) SUZUKI Takeshi  慶應義塾大学, 医学部, 講師 (80327600)
Project Period (FY) 2013-04-01 – 2016-03-31
Keywordsカテコラミン / 敗血症 / 腸内細菌 / 腸管免疫機構
Outline of Final Research Achievements

Although the present study demonstrated that high concentoration of norepinephrine stimulated bacterial proliferation of Escherichia coli and Staphylococcus epidermidis from clinical specimen, the concentrations of catecholamine in gut lumen were relatively low in sepsis. These datas suggest that endgenous catecholamine has little effects to modify intestinal badterial flora and gut immune systems.

Free Research Field

麻酔学・集中治療医学

URL: 

Published: 2017-05-10  

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