2015 Fiscal Year Final Research Report
Study on the influence of disinfection reactants, and their time-variation in soil after disinfectant spraying.
| Project/Area Number |
25340102
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Environmental risk control and evaluation
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| Research Institution | Azabu University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 消毒剤 / 土壌 / 副生成物質 / 変異原性 / 消長 |
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| Outline of Final Research Achievements |
The impact on the soil environment of disinfectants used in dairy-related facilities for preventing the spread of infections has been examined. Several soil samples were collected from surrounding area. Disinfectants containing chlorine, alkaline disinfectants, and combination drugs, were sprayed on these soil samples. Organic matter in the soil disinfectant reactant compounds was extracted by the ultrasonic extraction method, using 7 organic solvents respectively. As a result, high mutagenic activity such as acetone was detected of in several solvent extracts to chlorine-based disinfectants. And there were many cases of direct acting mutagens causing base pair changes. Mutagenic by-products in soil tend to decrease over time, so even the particularly high mutagenic activities was reduced by more than about 80% after 1 year. The products were analyzed using a GC-MS, which suggested that several chemicals showing mutagenicity such benzaldehyde were present.
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| Free Research Field |
獣医公衆衛生学
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