Can oral administration of TG type gamma-linolenic acid improve the lypodystrophy?

2015 Fiscal Year Final Research Report

• Project/Area Number: 25350127
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Eating habits
• Research Institution: Nagasaki University
• Principal Investigator: OIKAWA Daichi 長崎大学, 教育学部, 准教授 (90571216)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: リポジストロフィー / 共役リノール酸 / TG型γ-リノレン酸 / 母子栄養

Outline of Final Research Achievements

In this study, we tried to improve the lipodystrophy syndrome derived from conjugated linoleic acid (CLA) by oral ingestion of "triacylglycerol (TG) type γ- linolenic acid (GLA)". The mitigation effect of the lipodystrophy syndrome was weaker at a dose of this TG GLA, ingested GLA was able to newly discovered that reducing the content ratio of the liver. In addition, CLA intake of the mother mice was found to induce lipodystrophy onset of pups. Moreover, it was found newly that TG GLA intake of mother mice were enhanced the inhibitory effect of lipodystrophy onset of male pups.

Free Research Field

食生活学