2015 Fiscal Year Final Research Report
Fruit jucie and its water insolbule fraction on insluin resistance
Project/Area Number |
25350175
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Eating habits
|
Research Institution | National Agriculture and Food Research Organization |
Principal Investigator |
SUGIURA Minoru 国立研究開発法人農業・食品産業技術総合研究機構, 果樹茶業研究部門カンキツ研究領域, ユニット長 (10355406)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Keywords | 果汁 / 不溶性画分 / インスリン抵抗性 / 糖尿病 / 糖負荷試験 |
Outline of Final Research Achievements |
It is widely known that the ingestion of fruit juice is one of the risk factor for developing insulin resistance. In this study, the effects of water insoluble fraction of fruit on postprandial blood glucose level and insulin resistance of normal and type 2 diabetic mice were examined. Postprandial blood glucose level after single oral administration of clear fruit juice not including water insoluble fraction was significantly inhibited in a dose-dependent way by adding water insoluble fraction of fruit. On the other hand, although chronic administration of clear fruit juice did not affect insulin resistance of type 2 diabetic mice, fruit juice including water insoluble fraction ameliorated insulin resistance in a dose-dependently manner. These results suggest that water insoluble fraction of fruit is an important factor for inhibiting postprandial blood glucose elevation and/or preventing insulin resistance.
|
Free Research Field |
食品科学
|