2015 Fiscal Year Final Research Report
Study on mechanisms of memory decline by magnetoencephalography
| Project/Area Number |
25350516
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OTSUKI Mika 北海道大学, 大学院保健科学研究院, 准教授 (10372880)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 短期記憶 / 加齢 / α波脳律動 / 脳磁計 / 初頭性・新近性効果 |
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| Outline of Final Research Achievements |
Magnetoencepahlograms during the performance of short-term memory tasks were compared between participants in their twenties (young) and sixties (aged). During the memorization of sequentially-presented memory items, displayed on a screen, the alpha-rhythm (8-13 Hz) amplitudes of young participants increased in corresponding with memory encoding process, while that of aged participants conversely decreased. Source estimation of the alpha-rhythm suggested that its increase was due to active inhibition of task-irrelevant visual inputs, and that aging may disable this active inhibition, thus causing memory decline.
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| Free Research Field |
生体医工学
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