Development of effective rehabilitation techniques for motor and cognitive function in the elderly

2015 Fiscal Year Final Research Report

• Project/Area Number: 25350601
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Kagawa University
• Principal Investigator: TOUGE TETSUO 香川大学, 医学部, 教授 (80197839)
• Co-Investigator(Kenkyū-buntansha): GO KEIRYU 岡山大学, 工学部, 教授 (30294648)
• Co-Investigator(Renkei-kenkyūsha): IKEDA KAZUYO 香川大学, 医学部, 病院助教 (30592315) ; KUME KODAI 香川大学, 医学部, 助教 (20592314)
• Research Collaborator: RI KI
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 経頭蓋脳磁気刺激 / 最大筋収縮 / 高齢者 / 認知機能訓練 / 運動機能訓練 / 事象関連電位

Outline of Final Research Achievements

In eight healthy adult subjects, transcranial magnetic stimulation with the maximum voluntary muscle contraction (TMS with MVC) was performed intermittently for 40 minutes. Digit span and digit-symbol coding of Wechsler Adult Intelligence Scale－Third Edition, motor evoked potentials, pinching muscle force and multimodality event related potentials (ERP) were measured before and after TMS with MVC. As a result, in comparison with the placebo group using false magnetic stimulation, the test group employing real magnetic stimulation was improved recalling a series of numbers in inverse order (P<0.05), and tended to be increased pinching muscle force. Although the potential related to multimodality cognition of ERP did not differ between the groups, we need further analysis for each ERP component. As a conclusion, the present result suggests that TMS with MVC can improve muscle force and verbal memory function.

Free Research Field

臨床神経生理学