2016 Fiscal Year Final Research Report
Analysis of developmental changes in suckling and chewing using decerebrated and arterially perfused rat preparations.
| Project/Area Number |
25350622
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 顎運動 / 舌運動 / 吸啜 / 咀嚼 / 呼吸 / 舌骨下筋群 |
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| Outline of Final Research Achievements |
In the present study, we developed a new experimental model using decerebrated and arterially perfused rat preparations to investigate neuronal mechanisms generating suckling and chewing. We first observed respiratory conditions in the preparations. As a result, the activity of the upper airway muscles in hypercapnic acidosis differs from that under normocapnic conditions. We next tried induction of suckling and chewing rhythms by electrical stimulation of the hard palate or application of NMDA. The rhythmic activity was induced by electrical stimulation or NMDA application in the masseter nerve and the mylohyoid nerve alternatively.
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| Free Research Field |
口腔生理学
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