2015 Fiscal Year Final Research Report
Behavioral training based on the reward and paired associative stimulation: improvement of reciprocal inhibition dysfunction
Project/Area Number |
25350632
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | Kitasato University |
Principal Investigator |
SUZUKI Makoto 北里大学, 医療衛生学部, 教授 (80554302)
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Co-Investigator(Kenkyū-buntansha) |
KIRIMOTO Hikari 新潟医療福祉大学, 医療技術学部, 教授 (40406260)
ONISHI Hideaki 新潟医療福祉大学, 医療技術学部, 教授 (90339953)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Keywords | 運動学習 / 経頭蓋磁気刺激 |
Outline of Final Research Achievements |
Reciprocal inhibition of antagonist muscles is crucial for motor learning in humans. Reward probability differentially altered behavioral probability and corticospinal excitability for reciprocal muscles, including the reward-related circuit. In addition, paired associative stimulation (PAS) is used to induce plasticity in the human motor cortex. Although reciprocal inhibition of antagonist muscles plays a fundamental role in human movements, (a) change in cortical circuits for reciprocal muscles by reward probability and (b) change in cortical circuits for reciprocal muscles by PAS are unknown. The results of this study implied that (a) reward probability differentially altered behavioral probability and corticospinal excitability for reciprocal muscles and (b) the cortical excitability for antagonist muscle within M1 decreased by PAS.
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Free Research Field |
臨床神経生理学
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