Development of an osteoporosis prevention program involving lipid metabolism disorder correction in postmenopausal women

2015 Fiscal Year Final Research Report

• Project/Area Number: 25350849
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Applied health science
• Research Institution: Okayama Prefectural University
• Principal Investigator: KUBOTA MEGUMI 岡山県立大学, 保健福祉学部, 教授 (80254564)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 閉経 / 女性 / 脂質代謝 / 骨密度

Outline of Final Research Achievements

The purpose of this study was to develop a osteoporosis prevention program to prevent the deterioration of dyslipidemia or arteriosclerosis and a decrease in the bone mineral density, contributing to the improvement of metabolic syndrome. Female rats were divided into the following groups:①SDT/OVX/high-fat diet、②SDT/OVX/ standard diet、③SD/OVX/ high-fat diet、④SD/OVX/ standard diet. I analyzed bone density, blood lipid, adiponectin, leptin and osteocalcin level. The increase in serum lipid concentration of the obese model rat was controlled menopause by an intake of the soy isoflavone. In addition, the suppressant effect of the drop of the bone density was accepted, too.

Free Research Field

複合領域